China (Mainland)
High Purity Sex powder Tadanafil Powder Tadalafil Tablets for ED CAS 171596-29-5 CAS NO.171596-29-5
- FOB Price: USD: 1,900.00-2,000.00 /Kilogram Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: T/T,MoneyGram
- Available Specifications:
AA(1-10)KilogramAA(1-50)KilogramA(1-50)Kilogram
- Product Details
Keywords
- high quality Calais
- High purity Tadalafil
- Cialis 171596-29-5 Supplier in China
Quick Details
- ProName: High Purity Sex powder Tadanafil Powde...
- CasNo: 171596-29-5
- Molecular Formula: C22H19N3O4
- Appearance: white powder
- Application: medical intermediate
- DeliveryTime: 3-15 working days
- PackAge: aluminium foil bag
- Port: any port in China
- ProductionCapacity: 1000 Kilogram/Week
- Purity: 99%
- Storage: dry and cool place
- Transportation: by air or boat
- LimitNum: 1 Kilogram
- Moisture Content: 0
- Impurity: 0
- 0: 0
Superiority
Our advantages
1, Rich Experience in produce----We have 26 years experiences in chemical products and 6years experiences in Pharmaceutical Intermediate products and APIS.
2, Competitive price ---We have the competitive price owing to low labor cos,t(we need large quantity).
3, Stable supply ability ---We have a stable supply ability owing to three workshops produce plan every month and stock plan for each products ;
4, Shipment Timely---The shipment never delayed and we can get reorder from new customer;
5, Rich experience in sales-- We have rich experience working with large international company.
6, Strong Quality Control System ---We have a very strong quality control system Raw material control / process control/ finished product quality inspection.
7. We Supply the Technology Support for Analyze and Synthesis and do new product according to customer's requirement.
8. Accept third lab test---We accept audit directly and tested . No any risk commitment for Customers.
9.Various payment terms---We can accept various payment terms include TT, and so on.
10,Our service---Free sample and 24 hours on-line professional service and other requirements
Applications:
Although sildenafil (Viagra), vardenafil (Levitra), and tadalafil (Cialis) all work by inhibiting PDE5, tadalafil's pharmacologic distinction is its longer half-life (17.50 hours) – compared to sildenafil (4.0–5.0 hours) and vardenafil (4.0–5.0 hours) – resulting in longer duration of action, and so partly responsible for "The Weekend Pill" sobriquet. Furthermore, the longer half-life is the basis for current investigation of tadalafil's daily therapeutic use in relieving pulmonary arterial hypertension. Sildenafil is approved in several world regions as a thrice-daily therapy for pulmonary arterial hypertension.
Specifications:
|
Test Items |
Specification |
Test Results |
|
Appearance |
White powder |
Conforms |
|
Test method |
High pressure liquid chromatography(HPLC) |
Conforms |
|
Melting Point |
300℃～303℃ |
301.5℃-302.6℃ |
|
Loss on drying |
≤0.5% |
0.24% |
|
Heavy metals(Pb) |
≤20ppm |
7.5ppm |
|
Residue on ignition |
≤0.1% |
0.08% |
|
Relative substance |
≤1.0% |
0.145% |
|
Assay (on dried basis) |
≥98.5% |
99.33% |
|
Conclusion |
The product conform to USP 32. |
|
Details
Welcome to Hebei Bosang International Trade Co.,Ltd.
Hebei Bosang International Trade Co.,Ltd. specializes in exporting high quality Pharmaceutical intermediates，Pharmaceutical raw materials，Phenylephrine，Safe Organic Solvents,HGH, Plant Extract, Spice Auxiliary and Hormones.
Our products are produced on the basis of best technical team, advanced equipment, high qualified management which meet the requirements of security and environmental protection. We earned customer trust and created a good reputation during these years.
Our company is always adhering to the ""open, flexible; integrity, and win-win"" business purposes and under the guidance of Business philosophy: "keeping credit, value quality, punctual delivery, favorable price “, continuously developing the excellent products, improving the service quality, putting efforts to expand the international market, we are committed to provide the excellent quality of products and the perfect services to the friends all over the world. We welcome all merchants to visit our company and talk over business with us!
We will provide the most comprehensive products and service to you! We are looking forward to your cooperation.
Tadalafil is an oral drug for the treatment of ED, used in the treatment of erectile dysfunction and premature ejaculation, erectile function impairment and premature ejaculation has very significant improvements. There are over 1500 documents to prove the caused by different causes impotence premature ejaculation, knew the success rate is above 80%, and show its reliable curative effect, through the use of more than 20 million people worldwide, proved its long-term stability, the safety of 25 to 60 minutes of work function to coincide with a time needed for foreplay, knew the time adjustment in the highest drug concentration time, help both husband and wife a satisfactory sex life.
Specification:
|
Items |
Specification of Standard |
Result of Analysis |
|
Appearance |
White Crystal Powder |
Passed |
|
Purity |
99.00% |
99.97% |
|
Melting Point(°C) |
107~109 |
108 |
|
Residual Solvents |
<0.3% |
0.01% |
|
Residue |
<0.3% |
0.01% |
|
Heavy Metals |
<10PPM |
5PPM |
| Tadalafil Basic information |
| Product Name: | 171596-29-5 |
| MF: | C22H19N3O4 |
| MW: | 389.4 |
| EINECS: | 200-835-2 |
| Product Categories: | Cnbio;Pyridines ,Halogenated Heterocycles;Intermediates & Fine Chemicals;API's;Inhibitor;Tadalafil;171596-29-5.mol |
| Safety Information |
| Hazard Codes | 11-20/21/22-36 |
| Safety Statements | 171596-29-5(Hazardous Substances Data) |
| MSDS Information |
| Tadalafil Usage And Synthesis |
| Indications and uses | Cialis (or Tadalafil) was developed by American pharmaceutical company Lilly. It is used to treat erectile dysfunction and belongs to a second generation of PDE5 inhibitors. Studies show that Cialis works very quickly, taking effect in around 15-20 minutes, and has a prolonged effect that can last for up to 36 hours. T1/2 is 17.5h. |
| Clinical Research | In a study of 348 cases of mild to severe erectile dysfunction, patients were randomly given 20mg of Cialis or a placebo. Results showed that in comparison to the placebo group, patients who took Cialis experienced improved intercourse success in the 24-36 hours following medication, with many patients achieving successful sexual intercourse twice in 36 hours. Side effect rate and severity were also no different from those of the placebo group. Over 5% of patients in the Cialis group experienced headaches and indigestion. |
| Side effects | No severe negative reactions. No perceived facial flushing or sight abnormalities following medication. Rare cases of headache and indigestion. |
| Warnings and precautions | Patients currently taking nitrates, experiencing angina pectoris, suffering from heart disease, patients who have unregulated hypertension or hypotension, or patients who have had a stroke in the past 6 months should not take Cialis. |
| Description | Tadalafil (market name “Cialis” or “Adcirca”) is a kind of PDE5 inhibitor used for the treatment of erectile dysfunction, benign prostatic hypertrophy and pulmonary arterial hypertension. The effect of Tadalafil is relaxing the blood vessels muscles and increasing the blood flow into the corpus cavernosum. The mechanism of action of tadalafil is through inhibiting the activity of the cGMP specific phosphodiesterase type 5 (PDE5). PDE5 degrades cGMP in the corpus cavernosum located around the penis. Therefore, tadalafi leads to the increased concentration of cGMP which further causes the smooth muscle relaxation and increased blood flow into the corpus cavernosum. Some clinical studies also implied that tadalafil could improve endothelia function in men with increased cardiovascular risk and lower the urinary tract symptoms secondary to benign prostatic hyperplasia. |
| Chemical Properties | White to Off-White Cyrstalline Solid |
| Uses | analgesic, norepinephrine uptake blocker, mu-opiod receptor agonist |
| Definition | ChEBI: A pyrazinopyridoindole that is 2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione substituted at position 2 by a methyl group and at position 6 by a 1,3-benzodioxol-5-yl group (the 6R,12aR |
| Brand name | Cialis (Lilly). |
| References | href="javascript:void(0);"br /> href="javascript:void(0);"br /> Roehrborn, C. G., et al. "Tadalafil administered once daily for lower urinary tract symptoms secondary to benign prostatic hyperplasia: a dose finding study." Journal of Urology 180.4(2008):1228. Rosano, Giuseppe M. C., et al. "Chronic Treatment with Tadalafil Improves Endothelial Function in Men with Increased Cardiovascular Risk." European Urology 47.2(2005):214-222. |
| Tadalafil Preparation Products And Raw materials |
Market :
Our Service
We offer specialized logistic service including export declaration,customs clearance and every detail during shipment,this makes us able to offer you one-stop service from the order to the products transported to your hand.
we will try our best to satisfied you:
1. Tailor-made for every customers.
2. Third-party test for the products you demand.
3. Test your counter-samples and produce them for you.
4. Best discount for old customers.
5.24 hours service.
payment way:
,moneygram ,T/T,btc ,and so on,
any question you can feel free to contact with us
Packing&Delivery
Package:20Kg Paper box or 25kg Paper barrel
|
By Courier |
By Air |
By Sea |
|
≤50kg |
50kg-500kg |
≥500kgs |
|
3-7 Days |
5-7 Days |
15-40Days |
|
Door to Door |
Airport to Airport |
Seaport to Seaport |
|
Easy to get products |
Need do custom clearance |
Need do custom clearance
|